How to Induce Muscle Hyperplasia: The Science

How to Induce Muscle Hyperplasia: The Science

Muscle hyperplasia was once thought to be impossible in humans. But with more and more research made available we might be ready to change our minds. 

Every bro worth his chalk knows that increasing muscle size through hypertrophy is the key to muscle growth. Lift heavy sh*t and you’ll be granted the gift of gains.

It’s as simple as that.

But delve deeper into the science and there might actually be more to the story. An increasing amount of research is coming out showing not only can you make your muscle fibers bigger… you might even be able to grow new ones too.

In this article we get all scientific on your ass and tell you exactly how to harness the solid power of hyperplasia.

Go forth and multiply…

Hypertrophy and Hyperplasia – The Science

As a reader of SpotMebro we’d like to think that you’ve graduated from schmedium stringers and are already rocking some pretty solid mass in an XL. If not, you better up your game bro.

If you lift weights on the regular you’ve noticed that after a few weeks of heavy training, your muscles increase in cross-sectional area.

Essentially, they look bigger, fuller and goddamn more aesthetic.

And as a a real lifter, you’ve likely heard of hypertrophy. If not, it simply refers an increase in muscle fiber size.

How does hypertrophy occur?

Through various chemical processes, lifting weights causes changes inside muscle cells that increase the size of muscle fibers. The functional compartments or ‘contractile proteins’ literally grow in size.

Once you overload a muscle through strength training, a cascade of events roll into play.

To be honest, we can’t fit all of them into an article like this, but here are the main ones you need to know about.

– Satellite cells located on the surface of the muscle fiber are activated after training. They respond to mechanical loading and muscle damage by multiplying so that they can fuse to the fiber and donate their nuclei. This increases the size of the contractile part of the muscle cell.

– Growth factors such as human growth hormone, hepatocyte growth factor and IGF-1 increase after hard strength training. As protein hormones they help trigger satellite cell activation and also help them find damaged cells to repair.

– Hormones such as testosterone increase after training too. They play an important part of muscle protein synthesis and the anabolic regulation of hypertrophy.

At the most basic level, muscles increase in size because of a load of different physiological processes coming together to help your muscles adapt to training.

You might also like : 5 tips on how to stay lean and shredded year round

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